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diabetes endocrinology potassium cardiology causes diagnosis differential dpp4 high management medications nephrology sglt2 summary table toxicity agonists allopurinol anthracycline antidote
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... to 15 g QD • Side ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... of use) Common Side ... #Pharmacology # ... Summary #DM2 #diabetes
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... with only few side ... #Renal #Dosing ... #Pharmacology #Management ... #Diabetes #DM2
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side ... #Pharmacology # ... Summary #DM2 #diabetes
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
: Treatment of Hyperkalemia ... oral suspension DOSING ... ACE inhibitors, ... Most common side ... #Pharmacology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... drugs include side ... #Pharmacology # ... Medications #DM2
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Poorly controlled DM ... NSAIDs • ACE Inhibitors
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Poorly controlled DM ... NSAIDs • ACE Inhibitors
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Common side effects ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products Angiotensin-Converting Enzyme Inhibitors (ACEIs) • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... Licorice - Causes hypokalemia ... Monoamine Oxidase Inhibitors ... Bilberry, Danshen, Dong ... supplementals #herbal #pharmacology
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