11 results
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... of use) Common Side ... #Pharmacology # ... Summary #DM2 #diabetes
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... with only few side ... #Renal #Dosing ... #Pharmacology #Management ... #Diabetes #DM2
Acyclovir - Pharmacology Summary

 • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Acyclovir - Pharmacology ... - selectively inhibits ... against CMV) • Dosing ... Resistance • Toxicity ... #Acyclovir #Pharmacology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... failure Common Side ... #Pharmacology # ... Summary #DM2 #diabetes
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... drugs include side ... #Pharmacology # ... Medications #DM2
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
Common side effects ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
oral suspension DOSING ... ACE inhibitors, ... Most common side ... #Hyperkalemia #Pharmacology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... risk of digoxin toxicity ... increasing risk for toxicity ... Monoamine Oxidase Inhibitors ... supplementals #herbal #pharmacology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... Xanthine oxidase inhibitor ... chemotherapy Dosing ... : 100 mg/m2/dose ... CrCl <10mL/min Side
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
ineffective because MTX inhibits ... Leucovorin dosing ... , up to 100 mg/m2 ... evidence of marrow toxicity ... #Management #Pharmacology