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endocrinology acromegaly diagnosis feedbackloop growthhormone pituitary treatment
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... deficiency: - Short ... expansion (e.g. carpal ... tunnel, OSA, Incr ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Diagnosis and Management ... paresthesias (carpal ... tunnel) and OSA ... malignancy Pathophysiology ... glucose suppression test
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