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diagnosis hematology management differential druginduced lupus oncology anemia cancer chronic comparison dil hemolytic leukemia lymphocytic mds myelodysplasia myelodysplastic platelets polychondritis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... cells can indicate disease ... microglobulin Treatment ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... • Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease ... comparison #table #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell ... genotypes): SS, SC, SE ... Differential #Diagnosis #Algorithm ... #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... some time, let’s see ... As with many disease ... #workup #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... lymphoma • B cell ... Adenocarcinoma Treatment ... #Rheumatology #
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Epidemiology: -10% of all ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... Discontinuation of causal ... DrugInduced #Lupus #DIL #rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
multicentric Castleman disease ... erythematosus (SLE ... , Lyme disease, ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Males • Affects all ... cases such as: • SLE ... Sarcoidosis • Behcet disease ... affected tissue Treatment ... Polychondritis #rheumatology
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