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differential management rheumatology hematology monoclonal bee behcet cancer disease emergencies erythematosus gammopathy gravis lupus mgus myasthenia noninflammatory oncologic paraproteinemias significance
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... of breath • Neurologic ... Sausage-like" hemorrhagic retinal ... veins, serum viscosity ... #differential #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... skin injury) • Neurologic ... (Clinical Dx). ... : Giant retinal
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Neurologic-Centered ... capillary leak syndrome ... #hematology #oncology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
important, as early diagnosis ... • Genetic • Retinal ... MRI lesions and clinical ... consistent with MS ... #neurology #noninflammatory
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Hypergammaglobulinemic macular ... , retinal, DVT, ... #Differential #Diagnosis ... #Oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia #Gravis #diagnosis ... #management #neurology
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Syphilis - Clinical ... Albuminuria, nephrotic syndrome ... Headache, meningitis, ocular ... ulcerated • MSK ... Syphilis #stages #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... Differential Diagnosis ... Clinical Features ... artery or vein
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... gland) biopsy • Ocular ... RTA, TYPE I RTA Diagnosis ... salivary ducts Clinical ... phenomenon (16%) MSK
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