10 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... 4) progressive muscular ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Cathepsin G release → vascular ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... • Mutism Pathophysiology ... • Examine for signs ... Arms extended; wrists ... #PhysicalExam #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Behcet disease) Differential ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
Diagnosis and Management ... duodenum Clinical Signs ... • Should be on differential ... Pathophysiology: ... #Summary #vascular
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Reversible course Differential ... Syndrome #diagnosis #management ... #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... very remarkable w/differential ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... pulse deficits vascular ... affects the skin, neurologic ... #Diagnosis #Rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... Myelitis #diagnosis #management ... #neurology #differential
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Cataracts - Macular ... positive Romberg sign ... Falls #Diagnosis #Differential ... #Evaluation #Geriatrics ... #Neurology