14 results
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... joints (shoulders, wrists ... • Underlying disease ... states Pathophysiology ... #rheumatology #
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Systemic Rheumatic Disease ... Sclerosis, Sjogren's Disease ... Crystal Arthropathy: Gout ... , CPPD • Seronegative ... Differential #Diagnosis #rheumatology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... • Gouty tophus ... Arthritides (RA, CPPD ... diffuse chondral disease ... diagnosis #msk #rheumatology
Monoarthritis - Differential Diagnosis
Infection (Acute):
 - S. aureus (most common)
 - S. pneumonia
 - Salmonella (in
species - Lyme disease ... Coccidioidomycosis Crystal - Gout ... birefringent - CPPD ... involve the b/l wrists
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... joints (shoulders, wrists ... often involves the wrists ... atypical locations: Wrist ... #Rheumatology #
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... ) (tends to be out ... affected — e.g., wrist ... #Disease #Signs ... #Symptoms #Pathophysiology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
produced, incr gut ... pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... distal to elbows/wrists ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
Common Forms of Arthritis in the Hands

Acute Rheumatoid Arthritis 
Tender, painful, stiff joints in rheumatoid arthritis,
metacarpophalangeal, and wrist ... joints in acute disease ... Chronic Tophaceous Gout ... chronic tophaceous gout ... #Hands #Types #Rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... reactive arthritis, gout ... Inflammatory, crystalline disease ... Joint #Pain #MSK #rheumatology ... #approach #workup