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hematology management rheumatology differential leukemia algorithm antimda5 antimda5dm antinxp2 antinxp2dm aplastic canimorsus capnocytophaga chronic clinical cll erythematosus gap globulin hodgkins
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... ulcerations • Skin ... #rheumatology #dermatology ... #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... deficiency Work ... cryoglobulins • Skin ... #dermatology #physicalexam
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... #dermatology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Headaches • Pale skin ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... dogs & latter can cause ... gram-negative bacillus cause ... the key to the diagnosis ... #Rash #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... ) Classification ... Hodgkin Lymphoma Workup ... #classification ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Differential Diagnosis ... Still disease, dermatomyositis ... lymphopenia, low PLT • Anemia
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... Muscle atrophy may cause ... : • ILD was diagnosed ... #rheumatology #dermatology
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