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hepatology algorithm causes lfts ascites obstetrics abnormal albumin biliary chemistry cholangitis cirrhosis comparison enzymes gradient hellp hypertension icp injury interpretation
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... Hepatitis, Preeclampsia ... #Fatty #Liver #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Liver of Pregnancy ... #Disease #Pregnancy ... #comparison #differential ... #diagnosis #icp
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Alcoholic hepatitis ... - Acute fatty ... liver of pregnancy ... #differential #
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
) - Differential ... Diagnosis High ... - Alcoholic hepatitis ... - Acute fatty ... liver of pregnancy
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... HTN: ascites (SAAG ... Cirrhosis/acute hepatitis ... metastasis • Fatty ... liver of pregnancy
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... melanoma, myeloma • Pregnancy ... #differential # ... diagnosis #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease ... • Alcoholic hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... of cholestatic disease ... disease: > 2 ... #chemistry #diagnosis ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
obstruction • ALP ... or higher • Liver ... bile ducts Differential ... Viral hepatitis, ... cholestasis of pregnancy
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... disease; AST, aspartate ... non-alcoholic fatty ... liver disease; ... #Enzymes #Differential
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