11 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... ) Pathophysiology ... : • Defect in fetal ... infiltration) Differential ... #Pregnancy #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Malignancy, 1° PBC ... Toxic: Medication, Pregnancy ... #Injury #Differential ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... melanoma, myeloma • Pregnancy ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... post-partum • Typical clinical ... and hemorrhage Acute ... #hepatology #obstetrics ... hepatitis #comparison #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Hepatocellular - Check Acute ... Mixed - Check Acute ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... or higher • Liver ... bile ducts Differential ... cholestasis of pregnancy ... diagnosis #workup #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... • Cirrhosis/acute ... of pregnancy ... Diagnosis #causes #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Intravenous Drug Use • Pregnancy ... Syndrome, Ischemic Liver ... Venous #Arterial #pathophysiology ... #hematology #differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... appreciate the value ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Framework and Clinical ... utilization: - Pregnancy ... liver failure: ... beriberi #nutrition #pathophysiology