9 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... : • Defect in fetal ... Diagnosis: Viral Hepatitis ... #hepatology #obstetrics
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... (AFLP) • Onset ... #hepatology #obstetrics ... #hepatitis #comparison ... diagnosis #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune: Autoimmune hepatitis ... melanoma, myeloma • Pregnancy ... Chronic viral hepatitis ... liver #injury #hepatitis ... diagnosis #algorithm #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... of Alcoholic Hepatitis ... >1.5, and both values ... Possible ischemic hepatitis ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... >1.5, and both values ... Possible ischemic hepatitis ... #Diagnosis #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
obstruction • ALP ... Diagnosis: • Viral hepatitis ... cholestasis of pregnancy ... diagnosis #workup #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... Cirrhosis/acute hepatitis ... Fatty liver of pregnancy ... Diagnosis #causes #hepatology