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differential liver algorithm lfts hepatitis obstetrics acute causes chemistry comparison dermatology dermatosis disease fatty febrile hellp hematology icp injury interpretation
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Elevated Liver enzymes ... (AFLP) • Onset ... #hepatology #obstetrics ... #differential #diagnosis ... #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... disease US — Normal ... Others #LFTs #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... : • Defect in fetal ... #hepatology #obstetrics ... #obgyn #diagnosis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
metabolic syndrome criteria ... the magnitude of enzyme ... ALP, alkaline phosphatase ... #Algorithm #Hepatology ... #Liver #Enzymes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... • Near normal ... Source of Liver Enzyme ... liver #chemistry #diagnosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... function may be abnormal ... Source of Liver Enzyme ... #algorithm #hepatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... inflammatory disease, or pregnancy ... Abnormal laboratory ... values at presentation ... #Diagnosis #Hematology
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