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hepatology algorithm differential lfts causes liver transaminitis abnormal alkaline alp chemistry cholangitis elevated elevation hepatitis hypertension injury interpretation liverenzymes liverfunctiontests
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Diagnose PBC if ... #PBC #Primary ... #Biliary #Cirrhosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... AIH, Wilsons, Pregnancy ... Ducts - PBC ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... cholestasis of pregnancy ... #Biliary #Cirrhosis ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... - Drugs - Pregnancy ... - Drugs - Primary ... (PBC) - Other ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Autoimmune hepatitis, PBC ... melanoma, myeloma • Pregnancy ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Wilson's • Pregnancy ... - AFLP, HELLP ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Duct Stone • Biliary
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... /acute hepatitis ... Fatty liver of pregnancy ... • Primary biliary ... #causes #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... Mixed - Check Acute ... hepatitis: < 1 • Cirrhosis ... liver #chemistry #diagnosis ... #differential #Hepatology
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... /or prognostic criteria ... line therapy if ALP ... survey disease #PBC ... #Primary #Biliary
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