20 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... Pregnancy (AFLP) ... child * Severe cases ... TTPHUS #HELLP #AFLP ... obstetrics #hematology #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... = nonspecific (nausea ... infiltration) Differential
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... Pregnancy (AFLP) ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Vascular Causes ... of Acute Liver ... melanoma, myeloma • Pregnancy
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... Intestine - Other causes ... - Drugs - Pregnancy
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Wilson's • Pregnancy ... - AFLP, HELLP ... #Causes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Hepatocellular - Check Acute ... Mixed - Check Acute ... #chemistry #diagnosis ... #differential #
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Diagnosis #Causes
Causes of Gallbladder Wall Thickening
Primary Wall Thickening:
1 . Acute calculous cholecystitis
2. Acute acalculous cholecystitis
3. Chronic cholecystitis
4.
Causes of Gallbladder ... Systemic Processes: Liver ... Dengue fever, Pregnancy ... #differential # ... diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... • Cirrhosis/acute ... of pregnancy ... #Diagnosis #causes