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diagnosis differential algorithm thrombocytopenia workup arteritis chronic comparison disease disorders evaluation extravascular falls fatigue gca geriatrics giantcell headaches hemolysis hemolytic
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... • Rheumatoid Arthritis ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
function test, ANA (e.g ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... - Infection (e.g ... syphilis, and HIV ... Impotence - Saddle anesthesia ... loss - Saddle anesthesia
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... systemic complaints- anemia ... identifies 85 to 95% of cases
Headaches Overview - Primary vs Secondary Headaches What’s the Core Difference? • Primary headache = headache is
What’s the Core ... • Vascular (e.g ... (e.g., temporal ... (e.g., seizures ... loss, cancer, HIV
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Additional tests: HIV ... inflammatory disease (e.g ... Chemistry profile (e.g
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
Cardiac arrhythmias (e.g ... embolism - Severe anemia ... Peripheral neuropathy (e.g ... - Rheumatoid arthritis ... Joint instability (e.g
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