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differential management algorithm disorders syndrome thrombocytopenia blood classification clinical common comparison distribution elevation eosinophil eosinophilia erythema essential et gangrenosum hemophilia
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Mnemonic NO cause ... Drugs (antibiotics e.g ... Viral: HSV, EBV, HIV ... #Differential #Diagnosis ... #Dermatology #SkinRash
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Quinidine • HIT ... Foreign Surface (e.g ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... perfusion - shock->treatments ... before beginning treatment ... Ethylene glycol - HIV
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... hemophilia type (e.g ... by a hemophilia treatment ... #Management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... #Dermatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Thrombosis (e.g ... ET-associated mutation (e.g ... thrombocytosis (e.g ... Thrombocythemia #ET #hematology ... #hematology
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