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diagnosis coagulation differential abnormal treatment activation dic disorders disseminated hemophilia intravascular macrophage mas platelet rheumatology syndrome thrombocytopenia
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... to one factor e.g ... PT and aPTT 1. ... #aPTT #Prolonged ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... inhibitory drugs (e.g ... #aPTT #Prolonged ... #differential #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
is prolonged, but ... normal in mild cases ... ) • PT/INR & von ... hemophilia type (e.g ... #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... #treatment #management ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... Hypofibrinogenemia • ↑ PT ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
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