29 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual ... diagnosis #management #neurology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... translocation • Types: Classification ... Malignancies (eg
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
pylori test (GI symptoms ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
metastases, Infection (e.g ... uropathy, Metabolic causes ... (e.g., hypokalemia ... disease, Drugs (e.g ... #Types #Nephrology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
• Meningeal signs ... ) • Systemic symptoms ... and signs (e.g. ... CNS infection (e.g ... Diagnosis #Algorithm #neurology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... but in severe cases ... May be 10 (eg direct ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... brainstem syndromes (e.g ... AQP4-lgG disease; e.g ... Manifestations #diagnosis #neurology ... #symptoms #signs
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
general seizure caused ... and metabolic causes ... Pseudoseizures #GrandMal #Classification ... #Diagnosis #Neurology ... #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology