42 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... involvement: Intractable nausea ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... #symptoms #signs
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Pathophysiology: ... #PhysicalExam #clinical
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG
Case – 26M with no medical history presents with chest pain and palpitations. He states that
denies associated symptoms ... second most common cause ... cardiac death in young ... #Clinical #Cardiology ... #ECG #EKG #ARVD
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
cardiac syncope, e.g ... carotid sinus syndrome ... orthostatic vital sign ... and an initial ECG ... should be guided by clinical
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Pathogenesis and clinical ... most common in young ... to the femur ( e.g ... #differential #causes ... #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... • Meningeal signs ... ) • Systemic symptoms ... and signs (e.g. ... CNS infection (e.g
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... hyperthermia crisis (late sign