12 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Presentation - Young ... • Or brainstem syndromes ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... , Myasthenia gravis ... #symptoms #signs
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Serologic and EMG ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... diagnosis #management #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral Sclerosis ... Pathophysiology ... - Causes progressive ... EMG: LMN Signs in ... #neurology #diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG ... disease, Multiple sclerosis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... electromyographic (EMG ... Differential #Diagnosis #neurology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... symptoms are not caused ... of diagnosis (e.g ... anterior/posterior MSK ... Diagnosis #Management #Signs
Emergent Causes of Headache and Associated Risk Factors
Carbon monoxide poisoning
 - Breathing in enclosed or confined
Emergent Causes ... carbon monoxide (eg ... living conditions (eg ... vascular diseases (eg ... of the body - Young
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... suggestive of multiple sclerosis ... : - Multiple sclerosis ... optica (NMO)