9 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... • Myasthenia Gravis ... Lambert-Eaton Myasthenic Syndrome ... #Weakness #Neurology ... #Differential #
Peripheral and Central Causes of Vertigo
Peripheral Causes (Common):
 - Labyrinth: Benign paroxysmal positional vertigo, Méniére disease,
Peripheral and Central ... Peripheral Causes ... often classified as ... #Causes #differential ... #diagnosis #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
(AG) = {Na - (Cl ... D-lactate (short bowel syndrome ... Neuromuscular weakness ... gravis) - Obstructive ... Diagnosis #Summary #Nephrology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... , Myasthenia Gravis ... #Causes #differential ... #diagnosis #neurology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia Gravis ... non-localized EOM weakness ... and anti-ACh antibodies ... tumor, and always ask ... ophthalmology #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Limb- proximal weakness ... life-threatening Differential ... PCB variants of GBS ... immunologic assay - MuSK ... diagnosis #management #neurology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology ... #differential #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Lesions Of The Peripheral ... Postsynaptic: Myasthenia Gravis ... #Differential # ... Diagnosis #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... cross-reacts with peripheral ... or the axon of peripheral ... Guillain #Barre #Syndrome ... diagnosis #management #neurology