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diagnosis hematology management tumor apml classification clinical differentiation friction gravis hodgkins iliotibial itband leukemia leukostasis lymphoma mds myasthenia myelodysplasia myelodysplastic
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... and AML) and solid ... Walid Malki, MD, MS ... #Syndrome #TLS ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... have fever - ACS ... leukapheresis - TLS ... #Syndrome #TLS ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... & DIC • Tumor lysis ... syndrome: Develops ... #Oncology #Diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
muscles: “myasthenic crises ... life-threatening Differential ... Generalized fatigue - ALS ... immunologic assay - MuSK ... Myasthenia Crises
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Iliotibial Band Friction Syndrome - MSK Radiology Imaging Findings: • The iliotibial band (ITB) is thickened with
Friction Syndrome ... - MSK Radiology ... Case description ... • Treatment: Conservative ... Differential diagnosis
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