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diagnosis hematology management apml chronic classification dermatologic dermatology differentiation erythematosus gap globulin granulomatosis leukemia lupus lymphocytic mds monoclonal myelodysplasia myelodysplastic
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... Lymphoma - Comparison ... Hodgkin's Lymphoma ... , ALL) • Solid ... #comparison #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... accounts for 10% of all ... Immunohistochemical studies (to differentiate ... Lymphoma Treatment ... #oncology #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... lymphoma SLL ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
reticularis Differential ... • Goodpasture syndrome ... disease • Non-Hodgkin ... lymphoma (lymphomatoid ... rash #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... (HCV) • CLL & ... Evans • ITP • Cl-NH ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... • Induce blast cell ... initiation • Differential ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... lymphoma • Evans ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Amyloidosis • Lymphoma ... changes (POEMS syndrome ... Castleman disease • AL ... : Lymphoma, Leukemia ... #ProteinGap #differential
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Males • Affects all ... Viral infection • Lymphoma ... • GPA/EGPA • ... affected tissue Treatment ... Polychondritis #rheumatology
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