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hematology algorithm ammonia cancer comparison differential differentiation gout hyperammonemia leukemia management mds myelodysplasia myelodysplastic syndromes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... #APML #diagnosis ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... • Metabolic syndrome ... • Medications ... Gout #Comparison #rheumatology ... #Diagnosis
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
ileal conduit - Medications ... myeloma, CML, AML ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... progression to AML ... #diagnosis #hematology ... #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... Myelodysplastic syndromes ... myeloid leukemia (AML ... cytopenias and AML ... median age at diagnosis
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