11 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... organ damage • Treatment ... : • Pathophysiology ... TLS #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... Pathophysiology ... APML #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... complete paralysis of all ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
Intraoperative Hypertension ... reservoir bag and APL ... overload / TURP syndrome ... #Checklist #Diagnosis ... #Management #Workup
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Intraoperative ... remember to tailor treatment ... reservoir bag and APL ... #Checklist #Diagnosis ... #Management #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
Intraoperative Tachycardia ... remember to tailor treatment ... reservoir bag and APL ... #Checklist #Diagnosis ... #Management #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... trolley, anaphylaxis treatment ... pack. ❸ Remove all ... #Checklist #Diagnosis ... #Management #Workup
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... 10d, venous (DVT/PE ... ♀, ↑Age, ESRD Pathophysiology ... D/c all heparin ... #Treatment #Hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... circulation: MCA ACA ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome ... #diagnosis #management