14 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
growth hormone (GH ... ) from the pituitary ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Sellar / Pituitary Mass - Differential Diagnosis Algorithm
Adenoma - Primary Anterior Pituitary
 - Secreting
Sellar / Pituitary ... Differential Diagnosis Algorithm ... Prolactin • GH ... Differential #Diagnosis #Algorithm ... #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
masses of all sizes ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... pituitary adenoma ... • Pituitary ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Algorithmic Approach to Hypothyroidism - Differential Diagnosis and Management Framework

Central Hypothyroidism (Secondary or tertiary) ↓TSH, ↓FT4
Algorithmic Approach ... ↓FT4 • Post-GH ... drug-induced • Pituitary ... Differential #Diagnosis #algorithm ... #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing Algorithm ... Growth Hormone (GH ... MRI to evaluate pituitary ... evaluation of other pituitary ... #diagnosis #endocrinology
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Hyperthyroidism → Signs ... Hyperthyroidism → MRI Pituitary ... Hyperthyroidism #algorithm ... #diagnosis #endocrinology