7 results
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... heart disease • All ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
masses of all sizes ... Signs / Symptoms ... Hyperprolactinemia • Diabetes ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... Stimulates Insulin, Inhibits ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... (EuDKA) SGLT2 Inhibitors ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... of Na+K+2Cl- Symport ... • Nephrogenic diabetes ... DDAVP) • Central diabetes ... Diuresis #Nephrology #Pharmacology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
endomyocardial biopsy Pharmacology ... : • ACE Inhibitors ... receptor-neprilysin inhibitors ... heartfailure #diagnosis #management ... #cardiology #pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... system (RAAS) inhibitor ... hypertension, diabetes ... after 4 cycles for all ... cardiology #oncology #pharmacology