24 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Diagnosis of ascites ... albumin gradient ... syndrome, Massive liver ... #albumin #gradient ... #hepatology #differential
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
Albumin Gradient ... Ascites is either ... made in the liver ... or not by the liver ... Interpretation #Differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... Gradient (SAAG) - Differential ... - Massive liver ... - Acute fatty liver ... #Differential #
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Acute fatty liver ... Mediterranean fever ... Causes #diagnosis #differential
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... INR, bilirubin, albumin ... sarcoidosis) • Liver ... metastasis • Fatty liver
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... Chylous <1% #Ascites ... #Differential #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... - Specific to liver ... Production: • Albumin ... chemistry #diagnosis #differential
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
: cell count + differential ... , albumin, protein ... culture • Serum-ascites-albumin-gradient ... ULN • Protein: level ... LVP > 5L: 25% albumin
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... - Differential ... disease • Acute liver ... amzn.to/2LmUODZ #Ascites ... #Differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... develops (DIC, ascites ... Transfer to a liver