755 results
Spontaneous Bacterial Peritonitis 
Clinical 
 • Fever 
 • Chills 
 • Abdominal pain 
Diagnosis
Peritonitis Clinical ... cephalosporin • Albumin ... SBP #Diagnosis #Hepatology
Ascites - Differential Diagnosis and Workup Algorithm

•
Perform paracentesis:
 • Cell count and diff 
 • Total
protein • Fluid albumin ... and serum albumin ... gastroenterology #hepatology
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG)

SAAG ≥ 1.1:
 • Cirrhosis
 • Portal
Serum Ascites Albumin ... #Table #Serum #Albumin ... Gradient #SAAG #hepatology
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
Serum to Ascites Albumin ... designed to keep albumin ... likely to allow albumin ... • Aka not much albumin ... liverprof #Diagnosis #Hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
serum ascites albumin ... SAAG #ascites #albumin ... #gradient #hepatology
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Proteins Pre-albumin ... Transthyretin) Albumin ... classification #Types #hematology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for Albumin ... terlipressin #Albumin ... Cirrhosis #treatment #hepatology
Hypoalbuminemia and hypophosphatemia can mask an anion gap (particularly, low albumin states usually underestimate the anion
hypophosphatemia can mask ... particularly, low albumin ... Multiply the albumin ... every g/dL the albumin
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... Mechanisms #DOAC #Hematology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
circulates with albumin ... Released from albumin ... AlkPhos #Bilirubin #Hepatology