814 results
Acute limb ischemia (ALI)

Rapid decrease in lower limb blood flow due to acute occlusion of peripheral
pathophysiology: ... #CLI #heparin #amputation
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
precursor protein mutations ... Presenilin 1 and 2 gene mutations ... AlzheimersDisease #Dementia #pathophysiology
Acute Limb Ischemia - Diagnosis and Management
#Diagnosis #Management #Algorithm #Limb #Ischemia #Ischemic #Amputation
Ischemia #Ischemic #Amputation
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
accumulation of genetic mutations ... #Pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... to inactivating mutations ... Gitelman #Syndrome #Pathophysiology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Marfan Syndrome - Signs and Symptoms

- Caused by mutations in the fibrillin-1 (FBN1) Gene (chromosome 15)
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- Caused by mutations
Diabetic foot infections (DFIs) is a common complication of longstanding diabetes, and it is associated with
lower extremity amputation ... on to require amputation ... lower extremity amputation ... lower extremity amputation
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
defect - Mutations ... ATPase - AEI mutations ... HTN (WNKI and 4 mutations
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... range of potential pathophysiologic ... - Pathophysiology