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management hematology dermatomyositis antimda5 antimda5dm antinxp2 antinxp2dm bleeding cushings disorders examination hemeonc hemophagocytic history hlh hypercortisolism infant leukostasis lymphohistiocytosis lysis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the face, or the anterior ... chest (in a V-sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involvement: May involve anterior ... Rule out other causes ... #Rheumatology # ... diagnosis #management ... #Dermatology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... #Cushings #Syndrome ... #signs #symptoms ... #endocrinology
Newborn Infant - Routine Examination Birthweight, gestational age and birthweight percentile are noted. General observation Of the baby's
is also a late sign ... When the diagnosis ... are observed for signs ... #Examination #Peds ... #Pediatrics #Diagnosis
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Marfan syndrome, ... Disorders #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
the face, or the anterior ... chest (in a V-sign ... Muscle atrophy may cause ... #management #rheumatology ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... patients with the HLH syndrome ... Presentation • Common Signs ... #Management #Hematology
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