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Central distribution is seen in sarcoidosis and cardiogenic pulmonary edema.
Peripheral distribution is mainly seen in cryptogenic
and cardiogenic pulmonary ... pneumonia and UIP ... #Diagnosis #Radiology ... #Pulmonary #HRCT ... Central #Peripheral #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... in many cases UIP ... #Diagnosis #Radiology ... #Pulmonary #CXR ... #Differential #RadiologyAssistant
UIP
UIP is a histologic pattern of pulmonary fibrosis.
On a chest X-ray UIP manifests as a reticular
pattern of pulmonary ... to confirm the diagnosis ... #Clinical #Radiology ... #CXR #UIP #Reticular ... #Honeycombing #RadiologyAssistant
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
is seen in: - UIP ... edema #Diagnosis ... #Radiology #Pulmonary ... #HRCT #ChestCT ... #Upper #Lower #RadiologyAssistant
Perilymphatic distribution
Perilymphatic nodules are most commonly seen in sarcoidosis.
They also occur in silicosis, coal-worker's pneumoconiosis and
in differential diagnosis ... thickening in the reticular ... #Diagnosis #Radiology ... #Pulmonary #HRCT ... #Differential #RadiologyAssistant
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
Lung cysts (LAM, LIP ... on the basis of HRCT ... #Diagnosis #Radiology ... #Pulmonary #CTChest ... Emphysema #SignetRing #RadiologyAssistant
Ground-glass opacity
Ground-glass opacity (GGO) represents:
- Filling of the alveolar spaces with pus, edema, hemorrhage, inflammation or
resolution of the HRCT ... predominance: UIP ... bronchiolitis #Diagnosis ... #Radiology #Pulmonary ... #Differential #RadiologyAssistant
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
morphologic findings on HRCT ... findings of NSIP, UIP ... #Diagnosis #Radiology ... #Pulmonary #CTChest ... ILD #Findings #RadiologyAssistant
Basic Interpretation
A structured approach to interpretation of HRCT involves the following questions:
What is the dominant HR-pattern:
reticular
nodular
high
interpretation of HRCT ... dominant HR-pattern: reticular ... bronchiectasis) #Diagnosis ... #Radiology #Pulmonary ... Algorithm #ILD #RadiologyAssistant
Septal thickening
Thickening of the lung interstitium by fluid, fibrous tissue, or infiltration by cells results in
in a pattern of reticular ... #Diagnosis #Radiology ... #Pulmonary #HRCT ... #CTChest #Reticular ... #Differential #RadiologyAssistant