9 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Most cases diagnosed ... mineralization Symptoms ... of Low Alkaline ... of Low Alkaline
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
C deficiency, anticoagulation ... • Weakness • Low-grade ... Serum DHEAS Diagnosis ... addisons #disease #endocrinology ... #diagnosis #signs
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... Adrenalitis Other causes ... ketoconazole, etomidate) Symptoms ... Hyperpigmentation is absent (low ... #Management #Endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
patient has good renal ... produces them when low ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
retroperitoneal masses ... Obstruction of blood flow ... #Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Hypercortisolism - Diagnosis ... levels following a low-dose ... the abdomen for adrenal ... #signs #symptoms ... #endocrinology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
acid, high LDH, low ... high d-dimer, low ... Treat underlying cause ... stenting - Consider anticoagulation ... Oncology #HemeOnc #Diagnosis
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... When present, symptoms ... MI, stroke, DVT/ ... appropriate only for low ... Hydroxyurea + anticoagulation
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
hormonal imbalances (low ... hormone levels cause ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry