5 results
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Syndrome (PRIS) ... Hyperlactatemia • Metabolic ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Clopidogrel (Plavix) and Clopidogrel Non-responders

Clopidogrel is an irreversible selective inhibitor of the platelet low-sensitivity adenosine diphosphate
to its active metabolite ... These include PPIs ... Nonresponders #pharmacology ... #toxicology
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Patterns of Toxic and Metabolic ... Symmetric Restricted Diffusion ... Vasogenic Edema: PRES ... MRI #Patterns #Toxicology ... #Metabolic #Brain
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
Metabolic Pathways ... Panel A shows the metabolic ... important target for antidotal ... Pathophysiology #Toxicology ... Osmolar #OsmolalGap #AnionGap
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion ... syndrome (PRIS) ... Versed) - CYP3A4 metabolism ... No pharmacologic ... (Haldol) - No pharmacologic