345 results
diagnosis differential clinical hepatology management hepatic liver pocus pharmacology ultrasound causes algorithm hematology pathophysiology anticoagulation doac signs neurology radiology table
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
Anticoagulants • Heparin ... Unfractionated heparin ... : Rivaroxaban, Apixaban ... , Edoxaban • Vitamin
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Warfarin - 100% Hepatic ... , 0% Renal Apixaban ... - 75% Hepatic, ... , 80% Renal Edoxaban ... - 50% Hepatic,
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban
Choice of anticoagulant for treatment of pulmonary embolism • Malignancy - LMWH • To avoid parenteral
- Rivaroxaban; apixaban ... - Rivaroxaban; edoxaban ... ; VKA • Hepatic ... Gl bleed - VKA, apixaban
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
Unfractionated Heparin ... Molecular Weight Heparin ... Bivalirudin, Dabigatran, Apixaban ... , Betrixaban, Edoxaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #inhibitor #Apixaban ... #Rivaroxaban #Edoxaban ... #heparin #pathway
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... , edoxaban (typically ... unfractionated heparin ... cause e.g. heparin ... thrombin inhibitors, heparin
Atrial Fibrillation (A-Fib) Summary Symptoms: • Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope. Why? Cardiac: • Valvular heart
Anticoagulation: • Initial heparin ... (rivaroxaban, apixaban ... , edoxaban) • Warfarin
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Rivaroxaban - Apixaban ... - Edoxaban Target ... #rivaroxaban #apixaban ... #edoxaban
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Thrombin Time, Ecarin ... Rivaroxaban Apixaban ... , Edoxaban Argatroban
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