5 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... #Workup #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... SLE], AOSD) • Infection ... with leukopenia, anemia ... ↑ PTT • ↑ Fibrin ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... of macrophages ... Cytopenia +++ (Plt ... Lymphohistiocytosis #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... hematology #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Triggers: ▪ Infections ... termed MAS-HLH: Macrophage ... - Cytopenias (anemia ... underlying trigger: Infections