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diagnosis hematology abnormal prolonged pt aflp bleeding bruising disseminated fatty hemostasis hepatology intravascular liver obgyn obstetrics pregnancy treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... protein C and S Pathophysiology ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #treatment #management
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... typically prolong aPTT ... and aPTT 1. ... (DIC) c. ... #differential #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
and aPTT If the ... PT and the aPTT ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... PTT suggests liver ... discern these causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... rapidly develops (DIC ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential
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