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hematology coagulation anticoagulant anticoagulants apixaban cascade causes dic disseminated edoxaban effects heparin inhibitor intravascular laboratory macrophage mas models pathophysiology pathway
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Argatroban Dabigatran ... Anticoagulants #Tests #Anticoagulation ... #Testing #Diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
platelet #thrombin #clot ... #PT #PTT #diagnosis ... pathophysiology #anticoagulation ... anticoagulant #Warfarin #Dabigatran
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Hypofibrinogenemia • ↑ PT ... ↑ PTT • ↑ Fibrin ... #Syndrome #Diagnosis ... #Management #Hematology
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