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diagnosis coagulation prolonged abnormal algorithm obgyn obstetrics platelet treatment workup aflp aggregometry bleeding bruising classification dic disseminated fatty hemepath hemophilia
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PTT • Prolonged ... PTT, Normal PT ... #PT #INR #Differential ... #Hematology #coagulation ... #disorders
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... or if a primary hematologic ... #Differential # ... #Workup #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT ... #aPTT #Prolonged
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Prothrombin Time (PT ... typically prolong PT ... #differential # ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /NORMAL PTT: Suggests ... and the PTT suggests ... discern these causes ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... ) • PT/INR & von ... #treatment #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... Normal platelet, PT ... , PTT (diff from ... #hematology #hemepath ... #differential #
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... IVF or PO): The pt ... #ketones #differential ... #diagnosis #management ... #endocrinology
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