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diagnosis hematology differential algorithm hemolysis intravascular aafp classification disorders folate folicacid gap globulin hemolytic hodgkins homocysteine hospitalization key lymphoma macrocytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... Microangiopathic hemolytic anemia ... ) (e.g. lupus, CLL ... • Intrinsic RBC ... #Causes #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • Sickle cell ... elliptocytosis - RBC ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... Atlas • Microcytic ... , Disseminated intravascular ... coagulopathy (DIC) #RBC ... #Morphology #Atlas
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
(RBC = red blood ... the most likely cause ... recovery also causes ... of the initial work-up ... Homocysteine #Algorithm #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... changes), high MCV anemia ... not required in all ... #Workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... reflection of intravascular ... schistocytes, nucleated RBCs ... immune hemolytic anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
from blood to the extravascular ... phlebotomy/ blood work ... prolonged rest can cause ... lying down and can cause ... Hospitalization #causes
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... myeloma • Plasma cell ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell ... anemia • Other
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