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hematology differential oncology rheumatology disease approach bloodcell castleman classification erythematosus gap globulin hodgkins joint laboratory leukemia lupus lymphocytic lymphoma management
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... #differential #diagnosis ... hematology #microscopy #atlas
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... not required in all ... #Causes #Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Diagnosis: • ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... rheumatic fever • Chronic ... Send for cell count ... Like in this case ... rheumatology #approach #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Chronic ... metabolic or endocrine disorders ... #laboratory #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC ... with Lupus: • Chronic ... Erythematosus #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Connective tissue disorders ... (RA, Temporal arteritis ... anemia • Other ... #differential #diagnosis
CASTLEMAN DISEASE Disorder of the immune system with excessive production of IL-6 Castleman’s disease is a rare, heterogeneous
CASTLEMAN DISEASE Disorder ... CBC: Anemia and ... HHV-8 and HIV is crucial ... and may help in diagnosis ... Castleman #disease #diagnosis
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