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diagnosis hematology differential oncology lymphocytic rheumatology arthritis bloodcell dehydrogenase disease elevated erythematosus gap globulin hemeonc lactate ldh lupus management mds
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... hematology #microscopy #atlas
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... in adults • Disorder ... 5) Symptoms of anemia ... #Chronic #Lymphocytic
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... • Hemolytic Anemias ... paralyses CNS Disorders ... Lymphomas • Leukemias ... differential #diagnosis #Laboratory
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Workup: • Complete
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... with: • Minimal laboratory ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Chronic ... metabolic or endocrine disorders ... #workup #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... leukemia • Solitary ... Connective tissue disorders ... autoimmune hepatitis, PBC ... anemia • Other
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