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diagnosis hematology differential oncology algorithm chronic laboratory lymphocytic management rheumatology testing arthritis bands basophils bloodcell causes cell classification dehydrogenase disease
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... iron deficiency anemia ... hematology #microscopy #atlas
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... • Neutropenia, anemia ... leukemia #CLL ... #diagnosis #workup
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... Red cell distribution ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
as white blood cell ... (depending on cell ... Leukemoid reaction ... disorders: > 100,000 ... rickettsia infections, brucellosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... in adults • Disorder ... Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... marrow failure with anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Thrombocytopenia and Platelet Disorders ... Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... hypertension • Unusual RBC ... membrane disorder ... Diagnosis #Algorithm #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Workup: • Complete
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
concentrations in: RBCs ... • Hemolytic Anemias ... - Pernicious anemia ... paralyses CNS Disorders ... Lymphomas • Leukemias
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC
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