14 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... iron deficiency anemia ... hematology #microscopy #atlas
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... Red cell distribution ... (BM) ablative disorders ... Algorithm #Diagnosis #Workup
Diagnosing Brucellosis
Epidemiological Exposures
- Endemic Regions
- Clinical Micro Lab Technicians
- Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters
- Unpasteurized
Diagnosing Brucellosis ... Diagnostic Tests: - CBC ... + Chemistry: Anemia ... Diagnosis #Criteria #Workup ... #Testing
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoid malignancy (CLL ... • Symptoms of anemia ... • hemolytic anemia ... Positive Coombs testing ... Blood smear - RBC
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Lymphocytosis on CBC ... lymphoproliferative disorders ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
disorders • Selective ... autism spectrum disorder ... , anemia, edema, ... Loss of teeth Anemia ... beta-spectrin, which is crucial
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
as white blood cell ... (depending on cell ... myeloproliferative disorders ... rickettsia infections, brucellosis ... Improves after treating
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Neutropenia • Platelet Disorders ... Workup: • Complete ... Treatment: Goals: Treating