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diagnosis hematology differential chronic cll leukemia lymphocytic aplastic bloodcell boop cell classification cop cryptogenic gap globulin hemeonc hodgkins ild microscopy
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Chronic disease anemia ... IgM associated lymphoma ... disease, Malignant lymphoma ... hematology #microscopy #atlas
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... classification #hematology #oncology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... Lymphocytosis on CBC ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... to large cell lymphoma ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... +Organomegaly+↑RBC ... (-) hemolytic anemia ... Differential #Diagnosis #Oncology
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
other processes Workup ... to order: • CBC ... strep, HIV • CTD workup ... pneumonia, Pulmonary lymphoma ... ILD #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... autoimmune hepatitis, PBC ... • Hematology: Lymphoma ... Thalassemia, Sickle cell anemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... • CBC + diff • ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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