12 results
diagnosis differential oncology hemolytic agglutinin algorithm biliary bloodcell cell cholangitis chronic cirrhosis classification cll cold disease disorders extravascular gap globulin
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... IgM associated lymphoma ... disease, Malignant lymphoma ... differential #diagnosis #hematology ... #microscopy #atlas
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Diagnosis #Algorithm #workup ... #hematology #testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... e.g. lupus, CLL, lymphoma ... • Intrinsic RBC ... differential #diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... Positive Coombs testing ... Blood smear - RBC ... #hematology #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Proximal limb muscle wasting ... Endocrinopathy, Lymphoma ... cholangitis #diagnosis #workup ... #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... platelets - WBC ... classification #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... schistocytes, nucleated RBCs ... immune hemolytic anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... Lymphocytosis on CBC ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... skin that are caused ... Workup: • Complete ... Treatment: Goals: Treating ... Syndromes #diagnosis #hematology
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