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differential cell chronic classification gap globulin hemolytic hodgkins leukemia lymphocytic lymphoma macrocytic management microcytic microscopy morphology nomenclature plasmacytoma protein proteingap
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Bite Cell RBC: G6PD ... Diseases #Red #BloodCell ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... corpuscular (cell ... #Algorithm #Diagnosis ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... Consider sickle cell ... #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... Lymphocytosis on CBC ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • No CRAB - no anemia ... • CBC + diff • ... #Oncology #Diagnosis ... #Workup #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... leukemia • Solitary ... anemia • Other ... #differential #diagnosis ... #hematology
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