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hematology differential chronic lymphocytic macrocytic management aafp cell classification folate folicacid gap globulin hemeonc hemolytic hodgkins homocysteine lymphoma macrocytosis mds
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Diseases #Red #BloodCell ... #differential #diagnosis ... hematology #microscopy #atlas
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Neutropenia, anemia ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... corpuscular (cell ... #Algorithm #Diagnosis ... #Workup #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... (RBC = red blood ... of the initial work-up ... #Diagnosis #Macrocytosis ... #Workup #AAFP
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology ... #hemeonc #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Consider sickle cell ... #Algorithm #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Leukemia • Idiopathic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC ... classification #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... leukemia • Solitary ... autoimmune hepatitis, PBC ... anemia • Other ... #differential #diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... • CBC + diff • ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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