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diagnosis management blood differential disease glomerular nephrology nephrotic oncology product reactions rheumatology algorithm arthritis autoimmune classification disorders glomerulonephritis hodgkins initial
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... Pouchelon #Warm #Antibody
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... with or without platelet ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Platelet count ... anemia Indirect ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... Causes purpura & ... TRALI): Leading cause ... false negatives on testing ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Hyperkalemia: Citrate in RBCs ... false negatives on testing ... RBCs (stored at ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Workup: • Complete ... Treatment: Goals: Treating ... Syndromes #diagnosis #hematology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
LDH - Assess for hemolysis ... Reticulocyte count/platelet ... antigen, hepatitis C antibody ... infections are common causes ... #workup #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Complete blood count (CBC ... Arthritis #laboratory #workup ... #Rheumatology
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
LDH - Assess for hemolysis ... Reticulocyte count/platelet ... antigen, hepatitis C antibody ... infections are common causes ... glomerular #disease #workup
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