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differential algorithm rheumatology oncology dermatology disease generalized hemeonc hemolytic management pancytopenia pruritus secondary agglutinin arthritis biliary cholangitis chronic cirrhosis cll
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... smear, HIV/HCV testing ... changes), high MCV anemia ... unclear, or if a primary ... #Causes #Workup
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... and Primary Causes ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Eating disorders ... Acquired Aplastic Anemia ... Primary hematological ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Eating disorders ... Acquired Aplastic Anemia ... Primary hematological ... #Algorithm #Hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... (primary biliary ... #diagnosis #signs ... #symptoms #testing ... #workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... usually IgM) (e.g. primary ... • Intrinsic RBC ... #hematology #anemia
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... intralobular bile ducts causes ... Proximal limb muscle wasting ... Diagnosis: • ... #workup #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Cold Agglutinin Syndrome ... anemia • Cold ... Positive Coombs testing ... #hematology #diagnosis
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... frequently affected systems ... Better call hematology ... #Algorithm #workup ... #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #Algorithm #causes
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